Mendelian Genetics (College Board AP Biology)

Topic Questions

1a4 marks

A new species of fly was discovered on an island in the South Pacific. Several different crosses were performed, each using 100 females and 100 males. The phenotypes of the parents and the resulting offspring were recorded. 

Cross I: True-breeding bronze-eyed males were crossed with true-breeding red-eyed females. All the F1 offspring had bronze eyes. F1 flies were crossed, and the data for the resulting F2 flies are given in the table below.  

F2 Phenotype  Male Female
Bronze eyes 3,720  3,800 
Red eyes  1,260 1,320

Cross II: True-breeding normal-winged males were crossed with true-breeding stunted-winged females. All the F1 offspring had stunted wings. F1 flies were crossed, and the data for the resulting F2 flies are given in the table below.

  

F2 Phenotype  Male Female
Normal wings 1,160  1,320
Stunted wings 3,600 3,820 

Cross III: True-breeding bronze-eyed, stunted-winged males were crossed with true-breeding red-eyed, normal-winged females. All the F1 offspring had bronze eyes and stunted wings. The F1 flies were crossed with true breeding red-eyed, normal-winged flies, and the results are shown in the table below. 

 Phenotype  Male Female
Bronze eyes, stunted wings  2,360   2,220 
Bronze eyes, normal wings  220 300
Red eyes, stunted wings 260  220
Red eyes, normal wings  2,240  2,180 

What conclusions can be drawn from cross I and cross II? Explain how the data support your conclusions for each cross. 

1b4 marks

What conclusions can be drawn from the data from cross III? Explain how the data support your conclusions. 

1c4 marks

Identify and discuss TWO different factors that would affect whether the island’s fly population is in Hardy-Weinberg equilibrium for the traits above. 

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2a1 mark

qp7-2016-frq-ap-biology

In a certain species of plant, the diploid number of chromosomes is 4 (2n = 4). Flower color is controlled by a single gene in which the green allele (G) is dominant to the purple allele (g). Plant height is controlled by a different gene in which the dwarf allele (D) is dominant to the tall allele (d). Individuals of the parental (P) generation with the genotypes GGDD and ggdd were crossed to produce F1 progeny.

Construct a diagram below to depict the four possible normal products of meiosis that would be produced by the F1 progeny. Show the chromosomes and the allele(s) they carry. Assume the genes are located on different chromosomes and the gene for flower color is on chromosome 1.qp72-2016-frq-ap-biology

2b1 mark

Predict the possible phenotypes and their ratios in the offspring of a testcross between an F1 individual and a ggdd individual.

2c1 mark

If the two genes were genetically linked, describe how the proportions of phenotypes of the resulting offspring would most likely differ from those of the testcross between an F1 individual and a ggdd individual.

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3a1 mark

In the tongue sole fish (Cynoglossus semilaevis), sex is determined by a combination of genetics and environmental temperature. Genetically male fish have two Z chromosomes (ZZ), and genetically female fish have one Z chromosome and one W chromosome (ZW). When fish are raised at 22oC, ZZ fish develop into phenotypic males and ZW fish develop into phenotypic females. However, when fish are raised at 28oC, the Z chromosome is modified (denoted as Z*). Z* W individuals develop as phenotypic males that are fertile and can pass on the Z* chromosome to their offspring even when the offspring are raised at 22oC. A cross between a ZW female and a Z*Z male is shown in the Punnett square below.

  Z W
Z* Z*Z Z*W
Z ZZ ZW

Predict the percent of phenotypic males among the F1 offspring of the cross shown in the Punnett square if the offspring are raised at 22oC

3b2 marks

At least one Z or Z* chromosome is necessary for survival of the fish. A researcher crossed two fish and observed  a 2: 1 ratio of males to females among the offspring. Based on the information, identify the genotype the male parent in the cross. Describe ONE fitness cost to the female of mating with this particular male.

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