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Edexcel International AS Biology

Revision Notes

Home / International AS / Biology / Edexcel / Revision Notes / 1. Molecules, Transport & Health / The Circulatory System / 1.6 The Need for a Circulatory System


1.6 The Need for a Circulatory System


The Need for a Circulatory System

  • The cells of all living organisms need a constant supply of reactants for metabolism, e.g. oxygen and glucose
  • Single-celled organisms can gain oxygen and glucose directly from their surroundings and the molecules can diffuse to all parts of the cell quickly due to short diffusion distances
  • Larger organisms, however, are made up of many layers of cells, meaning that the time taken for substances such as glucose and oxygen to diffuse to every cell in the body would be far too long
    • The diffusion distances involved are too great
    • Large organisms often have high energy requirements, so the delivery of reactants for metabolism needs to happen quickly
  • To solve this problem their exchange surfaces are connected to a mass transport system, for example
    • The digestive system is connected to the circulatory system
    • The lungs are connected to the circulatory system
  • Mass transport is the bulk movement of gases or liquids in one direction, usually via a system of vessels and tubes
  • The circulatory system in mammals is a well-studied example of a mass transport system; the one-way flow of blood within the blood vessels carries essential nutrients and gases to all the cells of the body
  • Mass transport systems help to
    • Bring substances quickly from one exchange site to another
    • Maintain diffusion gradients at exchange sites and between cells and their fluid surroundings
    • Ensure effective cell activity by supplying reactants and removing waste products

The double circulatory system in mammals

Mammals have a circulatory system known as a double circulatory system; the blood travels around the body in two separate circuits known as the pulmonary and systemic circulation



  • 1. Molecules, Transport & Health
    • Biological Molecules
      • 1.1 The Importance of Water
        • 1.2 Saccharides
          • 1.3 Core Practical 1: Estimating the Concentration of Sugars & Starch
            • 1.4 Condensation & Hydrolysis
              • 1.5 Triglycerides & Ester Bonds
              • The Circulatory System
                • 1.6 The Need for a Circulatory System
                  • 1.7 Blood Vessels: Structure & Function
                    • 1.8 The Cardiac Cycle
                      • 1.9 The Role of Haemoglobin
                        • 1.10 Atherosclerosis
                          • 1.11 Blood Clotting
                          • Diet & Health
                            • 1.12 Reducing Risk Factors of CVD
                              • 1.13 Dietary Antioxidants & CVD
                                • 1.14 Core Practical 2: Investigate the Vitamin C Content of Food & Drink
                                  • 1.15 Interpreting Data on Risk Factors
                                    • 1.16 Designing Studies into the Effects of Risk Factors
                                      • 1.17 Perception of Risk vs Actual Risk
                                        • 1.18 Data on Cholesterol & Lipoproteins
                                          • 1.19 Data on Effect of Diet
                                            • 1.20 Treatments for CVD - Benefits & Risks
                                          • 2. Membranes, Proteins, DNA & Gene Expression
                                            • Gas Exchange, Cell Membranes & Transport
                                              • 2.1 Properties of Gas Exchange Surfaces
                                                • 2.2 Cell Membranes
                                                  • 2.3 Core Practical 3: Investigating Membrane Structure & Permeability
                                                    • 2.4 Osmosis
                                                      • 2.5 Diffusion, Facilitated Diffusion & Active Transport
                                                      • Proteins
                                                        • 2.6 Amino Acids, Proteins & Protein Structure
                                                          • 2.7 Enzymes - Roles & Modes of Action
                                                            • 2.8 Core Practical 4: Investigating the Rate of Enzyme Reactions
                                                              • 2.9 Nucleotides, DNA & RNA, Base Pairing
                                                              • DNA & Gene Expression
                                                                • 2.10 DNA Replication
                                                                  • 2.11 The Nature of the Genetic Code
                                                                    • 2.12 How Bases Code for a Polypeptide Chain
                                                                      • 2.13 Transcription & Translation
                                                                      • Inheritance
                                                                        • 2.14 Mutations
                                                                          • 2.15 Patterns of Inheritance & Sex Linkage
                                                                            • 2.16 Cystic Fibrosis
                                                                              • 2.17 Genetic Screening
                                                                                • 2.18 Ethical & Social Issues of Genetic Screening
                                                                              • 3. Cell Structure, Reproduction & Development
                                                                                • Cell Structure & Organisation
                                                                                  • 3.1 Cell Theory
                                                                                    • 3.2 Levels of Organisation of Cells
                                                                                      • 3.3 Eukaryotic Cells
                                                                                        • 3.4 The Rough Endoplasmic Reticulum & Golgi
                                                                                          • 3.5 Prokaryotic Cells
                                                                                            • 3.6 Electron Microscopy of Animal Cells
                                                                                              • 3.7 Microscopy: Magnification & Resolution
                                                                                                • 3.8 Core Practical 5 - Light Microscopy
                                                                                                • Reproduction & Inheritance
                                                                                                  • 3.9 Gene Locus
                                                                                                    • 3.10 Meiosis & Variation
                                                                                                      • 3.11 Mammalian Gametes
                                                                                                        • 3.12 Fertilisation - Mammals
                                                                                                          • 3.13 Fertilisation - Flowering Plants
                                                                                                            • 3.14 The Cell Cycle & Mitosis
                                                                                                              • 3.15 Core Practical 6: Observing the Stages of Mitosis
                                                                                                                • 3.16 Calculation of Mitotic Index
                                                                                                                  • 3.17 Stem Cells & Cell Potency
                                                                                                                    • 3.18 Cell Specialisation
                                                                                                                      • 3.19 Post-Transcriptional Changes to mRNA
                                                                                                                        • 3.20 Gene Interaction & Epigenetics
                                                                                                                          • 3.21 Polygenic Inheritance & Continuous Variation
                                                                                                                        • 4. Plant Structure & Function, Biodiversity & Conservation
                                                                                                                          • Plant Structure & Function
                                                                                                                            • 4.1 Plant Cell Structure
                                                                                                                              • 4.2 Electron Microscopy of Plant Cells
                                                                                                                                • 4.3 Starch & Cellulose: Structure & Function
                                                                                                                                  • 4.4 Properties of Cellulose
                                                                                                                                    • 4.5 The Vascular Structure of Plants
                                                                                                                                      • 4.6 Core Practical 7: Identifying Tissue Types Within Stems
                                                                                                                                      • Plants & Conservation
                                                                                                                                        • 4.7 Plant-Based Products for Sustainability
                                                                                                                                          • 4.8 Water & Inorganic Ions in Plants
                                                                                                                                            • 4.9 Core Practical 8: Determining the Tensile Strength of Plant Fibres
                                                                                                                                            • Plants & Bacterial Growth
                                                                                                                                              • 4.10 Bacterial Growth Conditions
                                                                                                                                                • 4.11 Plant Products with Antimicrobial Properties
                                                                                                                                                  • 4.12 Core Practical 9: Antimicrobial Properties of Plants
                                                                                                                                                    • 4.13 Development of Drugs & Drug Testing
                                                                                                                                                    • Classification & Biodiversity
                                                                                                                                                      • 4.14 The Three Domains of Life
                                                                                                                                                        • 4.15 The Variety of Life
                                                                                                                                                          • 4.16 Biodiversity & Endemism
                                                                                                                                                            • 4.17 Species Richness & Heterozygosity Index
                                                                                                                                                              • 4.18 Index of Biodiversity
                                                                                                                                                                • 4.19 Ecological Niches & Adaptations
                                                                                                                                                                  • 4.20 Hardy-Weinberg Equation
                                                                                                                                                                    • 4.21 Roles of Seed Banks & Zoos in Conservation


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                                                                                                                                                                  Author: Naomi

                                                                                                                                                                  Naomi graduated in 2007 from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications. Naomi has a little cat called Buzz, and enjoys knitting.


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