CIE IGCSE Biology

Topic Questions

4.1 Biological Molecules

1
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DNA is a large molecule made from two chains of nucleotides held together by cross-links between pairs of bases.

Which of the following is a correct base pair?

  • T with C

  • G with A

  • C with G

  • C with A

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2
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Which row shows the three main elements from the Period Table that are present in most molecules in living organisms?

A carbon oxygen nitrogen
B hydrogen carbon oxygen
C oxygen sulfur carbon
D hydrogen carbon nitrogen

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3
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Which statement is false?

  • Fatty acids are a type of lipid

  • Glucose is a monosaccharide

  • A triglyceride consists of three fatty acids and one glycerol molecule

  • Amino acids each have a side group (R) that distinguishes them from other amino acids

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4
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The drawing shows a food test being carried out in a laboratory.


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Which food test is being shown and which food group is being tested for?

  • Biuret test for proteins

  • DCPIP test for Vitamin C

  • Benedict's test for reducing sugars

  • Emulsion test for fats

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5
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Which row represents the three main constituents of a DNA nucleotide?

A  bases  phosphate  nucleus
B  deoxyribose sugar  nucleus  chromosome
C  bases  deoxyribose sugar  phosphate
D  phosphate  chromosome  bases

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1
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A group of students tested four different foods using some common food tests.

Their results are shown in the table below.

 

Benedict’s test

Biuret test

Iodine test

DCPIP test

A

brick-red

purple

brown

colourless

B

brick-red

blue

brown

colourless

C

blue

blue

black

blue

D

brick-red

blue

black

colourless

Which food contains reducing sugar and Vitamin C but not protein or starch?

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2
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The table below shows the elements and basic units used by cells to make large biological molecules. 

 

basic units

elements

large molecule

A

amino acid

carbon, hydrogen, oxygen, nitrogen

protein

B

glycerol

carbon, hydrogen, oxygen, nitrogen

fats

C

glycerol

carbon, hydrogen, nitrogen

fats

D

amino acid

carbon, hydrogen, oxygen

DNA

Which row of the table is correct?

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3
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Four foods were tested for the following food molecules:

  • reducing sugar using Benedict’s reagent
  • protein using Biuret solution
  • fat using ethanol
  • Vitamin C using DCPIP
 

colour of food test result

 

brick-red/orange

purple/lilac

colourless

milky-white

A

B

C

D

Which food contains sugar and Vitamin C?

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4
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The shape and structure of molecules allows them to carry out their specific functions. 

Which row of the table below correctly describes a feature of each molecule that makes it specific?

  enzyme antibody DNA
A binding site active site base order
B active site binding site base order
C active site base order binding site
D binding site base order active site

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5
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Which drawing represents the general structure of an amino acid molecule that would be found in Nature?


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1
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A strand of DNA is shown below:

T ― G ― A ― A ― C ― T ― A ― G ― C ― C

What would the correct order of bases be on the complementary strand of DNA?

  • A ― C ― T ― T ― A ― A ― T ― C ― G ― G

  • C ― A ― G ― G ― T ― C ― G ― A ― T ― T

  • T ― G ― A ― A ― C ― T ―  A ― G ― C ― C

  • A ― C ― T ― T― G ― A ― T ― C ― G ― G

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2
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Three statements about proteins are given below. 

  1. Different sequences of amino acids give different shapes to protein molecules.
  2. Amylase is made from a sequence of amino acids joined together forming a non-specific 3D shape. 
  3. When mixed with Biuret solution, there is a colour change from blue to purple. 

Which of the statements above are true?

  • 1 & 2 only

  • 1, 2 & 3

  • 1 & 3 only

  • 3 only

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3
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The table below lists three large molecules found in living organisms. 

Which row correctly describes the smaller molecules these substances are made from?

 

glycogen

cellulose

oils

A

glucose

glucose

glycerol

B

glycerol

starch

fatty acids

C

glycerol

glucose

glucose

D

glucose

starch

glycerol

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41 mark

Four statements about large biological molecules are given below:

  1. Proteins are made from a number of different amino acids.
  2. Both glycogen and starch are made from simple sugar base units.
  3. Fats are made from glycerol and fatty acids.
  4. Oils are made from glycerol only. 

Which of the four statements above is/are false?

  • 1 & 3 only

  • 2 & 4 only

  • 4 only

  • None of them

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5
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A student carried out two food tests on solution F to determine what food groups it contains.

 

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What food molecules does solution F contain?

  • Starch only

  • Starch and protein

  • Starch and Vitamin C

  • Protein only

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61 mark

A student mixes a food reagent with solution X in a test tube. 

They observe a positive test result when a cloudy emulsion forms. 

 

food reagent

food molecule present in solution X

A

ethanol

glycogen

B

Biuret

lipids (fats and oils)

C

Benedict’s solution

glycogen

D

ethanol

lipids (fats and oils)

Which row of the table below identifies the reagent used and molecule present in Solution X?

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7
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Which row of the table below correctly describes the role of cellulose, proteins and water in living organisms? 

 

cellulose

proteins

water

A

solvent

enzymes & antibodies

for chemical reactions

B

strengthens cell walls

to make fats & oils

solvent

C

strengthens cell walls

enzymes & antibodies

solvent

D

solvent

enzymes & antibodies

strengthens cell walls

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8
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The image below shows two molecules before and after chemical digestion by enzymes in the alimentary canal. 

4--image-2---molecules

Which letter(s) identify the product(s) of complete starch digestion?

  • G and F

  • H only

  • E only

  • E and H

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