CIE IGCSE Biology

Topic Questions

11.1 Gas Exchange in Humans

1a
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3 marks

A good blood supply is essential to the effective function of the lungs in mammals. 

Give three other features of the gas exchange system that enable a fast rate of gas exchange within the lung.

1b
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2 marks

State what is meant by the term concentration gradient in the context of human gas exchange.

1c
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2 marks

Part (a) mentions that a good blood supply is needed in the lungs.

State what is meant by a good blood supply and explain how this improves gas exchange.

1d
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2 marks

There is estimated to be a surface area of 4.2 m2 in the overall lung system of a typical new-born baby, around one twentieth of the overall surface area of a typical adult's lungs.

Calculate the overall surface area of a typical adult's lungs.

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2a
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1 mark

The following list contains structures found within the breathing system.

structure order
 bronchus  
 facial airways  
 alveolus  
 trachea  
 bronchioles  

Using the numbers 1 - 5, sequence the structures to indicate the order in which air passes through them during an exhalation.

2b
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2 marks

Place a tick () in the Table 1 below to indicate the name of the organ which governs the activity of the human breathing system.

Table 1

Lungs Diaphragm Trachea Ribs
       

Explain your choice.

2c
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2 marks

State the reagent used to test for the presence of carbon dioxide (CO2) in a sample of air, and the appearance of a positive result.

2d
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1 mark

State the number of times more carbon dioxide (CO2) is in exhaled air than in inhaled air.

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3a
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1 mark

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State the name of the tissue type that supports the trachea and prevents it from collapsing under changes of pressure. 

3b
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6 marks

Fig. 1 shows the human breathing system, with some of its organs labelled.

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Fig. 1

Complete the table below to identify structures 1 - 6 in Fig. 1.

Part Organ / Structure
1  
2  
3  
4  
5  
6  

3c
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2 marks

Fig. 2 shows two students working together in an experimental investigation into the human breathing system. 

The seated student has just completed a period of 5 minutes of vigorous exercise and is sitting down. His partner is taking measurements.q3c-gas-exchange-in-humans-cie-igcse

Fig. 2

Describe the two measurements being taken as shown in Fig. 2.

3d
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1 mark

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Fig. 3 shows a serving of boneless pork ribs as served in a restaurant.

The meat comes from the area between the ribs and the bones are removed before serving.

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Fig. 3

Name the type of tissue that the meat in this dish comes from. 

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1a
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2 marks

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Table 1 shows some data gathered from a person's thorax whilst breathing normally at rest.

Assume that each breath consists of an inhalation lasting 2·5 seconds followed by an exhalation, also lasting 2·5 seconds. 

The pressure scale is:
0 means atmospheric pressure
+ means greater than atmospheric pressure
- means lower than atmospheric pressure

The volume scale is:
0 means its smallest volume
+++ means its largest volume

Table 1

event thoracic pressure
(0 / + / -)
thoracic volume
(0 / + / ++ / +++)
 beginning of exhalation +++ +++
 end of exhalation, before inhalation
 begins
   
 1 second into exhalation    
 1 second into inhalation - + or ++

Calculate the person's breathing rate in breaths per minute. 

1b
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4 marks
Using your knowledge of breathing, complete the missing boxes in Table 1, using the same scale as in the partially completed table in part (a).

The scales are repeated below for ease of reference:

The pressure scale is:
0 means atmospheric pressure
+ means greater than atmospheric pressure
- means lower than atmospheric pressure

The volume scale is:
0 means its smallest volume
+++ means its largest volume

1c
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2 marks

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Exhalation can be described as a passive event.

Explain the term 'passive' in this context.

1d
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3 marks

Explain how muscles of the breathing system help to facilitate increased removal of carbon dioxide when undergoing vigorous exercise.

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2a
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2 marks

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A study was carried out that looked at the movement of the diaphragm during normal breathing.

Fig. 1 shows the diaphragm movement in a healthy 55-year-old male.

Wis-RR3o_h-2a

Fig. 1

Calculate the breathing rate of the individual shown in Fig. 1.

2b
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3 marks

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(i)
Identify the ventilation processes occurring at the stages marked X and Y in Fig. 1.

[1]

(ii)

For the stage marked Y on Fig. 1, name a muscle other than the diaphragm involved at this stage and identify its state. 

[2]

2c
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4 marks

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Fig. 2 shows the results of another participant in the study.

This individual is a 57-year-old male with emphysema, a lung condition that reduces gas exchange and causes significant illness.

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Fig. 2

(i)

Contrast the graph shown here with Fig. 1 as shown in part (a).

[2]

(ii)

Suggest an explanation for the differences between the graphs.

[2]

2d
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2 marks

Events such as surgical trauma or nerve degeneration can lead to weakness or even paralysis of the diaphragm.

Suggest the effect that this would have on ventilation.

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3a
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3 marks

Fig. 1 depicts a section of the human gas exchange system.

2-1

Fig. 1

State the name of Organ 1 and describe its role in breathing out.

3b
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4 marks

In normal and healthy lungs, an effective oxygen supply is maintained between the alveoli and the lung capillaries.

Describe and explain how this is maintained.

3c
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1 mark

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Fig. 2 shows the changes in the volume of air in a woman’s lungs while breathing.

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Fig. 2

Explain how Fig. 2 shows that the woman was breathing out between times W and X.

3d
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1 mark

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Muscle action during ventilation is described as antagonistic.

Outline what this means with reference to one example during breathing.

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1a
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3 marks

A study estimated the number of people with chronic obstructive pulmonary disease (COPD) in India. Data were collected from two groups of people, those who lived in cities and those who lived in villages.

Fig. 1 shows the results.

cie-igcse-2018-febmar-q2a

Fig. 1

Compare the number of people with COPD in cities with the number of people with COPD in villages.

Use the data in Fig. 1 to support your answer.

1b
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6 marks

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(i)

Explain how the body prevents particles in inspired air from reaching the gas exchange surfaces.

[4]

(ii)
State two ways in which the composition of inspired air differs from the composition of expired air.
[2]
1c
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2 marks

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Alveoli are well ventilated to provide efficient gas exchange.

(i)

State the name of the muscles that cause the ribs to move during ventilation.

[1]

(ii)

During inspiration the pressure and volume in the thorax changes.

State these changes.

[1]

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2a
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4 marks

Fig. 1 shows a diagram of the gas exchange system.

cie-igcse-2018-s2-may-p3-q6a-respiratory-system

Fig. 1

Complete the labelling of Fig. 1 using the words from the list.

bronchiole         diaphragm         intercostal muscle         trachea

2b
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2 marks
(b)

Alveoli are gas exchange surfaces.

State two features that make alveoli good gas exchange surfaces.

[2]
2c
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3 marks
(c)

There is less oxygen in expired air than in inspired air.

(i)

Describe two other ways in which expired air is different from inspired air.

[2]

(ii)

State the name of a process that uses oxygen in cells.

[1]
2d
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2 marks
(d)

State an example of a cell and an organ from the gas exchange system.

[2]

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3a
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2 marks

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A genetic condition called Canine Tracheal Collapse affects certain breeds of domestic dog.

Affected dogs experience difficulty in breathing due to a weakness in the walls of the trachea.

Suggest, with a reason, which type of tissue is affected by this genetic disorder. 

3b
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2 marks

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Table 1 shows some differences between inhaled and exhaled air.

Table 1

  Inhaled air Exhaled air
Oxygen content / % 21 16
Carbon dioxide content / % 0.04 4

 

Calculate the percentage difference in oxygen content of exhaled air compared to inhaled air. 

3c
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2 marks

The presence of bronchioles, alveoli and blood capillaries within a lung all reduce its overall volume.

Explain how these structures actually improve the performance of the lung as a gas exchange organ. 

3d
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3 marks

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Explain the roles of the cilia and mucus in protecting the breathing system.

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