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OCR Gateway GCSE Biology: Combined Science

Revision Notes

Home / GCSE / Biology: Combined Science / OCR Gateway / Revision Notes / 6. Global Challenges / 6.2 Feeding the Human Race / 6.2.2 Genetic Engineering


6.2.2 Genetic Engineering


Genetic Engineering

  • Food production can be intensified (making more food with fewer resources) by an artificial process called genetic engineering
  • This involves taking genes from one organism and placing them into the cells of another organism (another species)
    • In doing so, this gives the new organism a new characteristic that it would not have developed naturally
  • Genetic engineering can be defined as follows:
    • A process which involves modifying the genome of an organism to introduce desirable characteristics
  • Specifically, genetic engineering is changing the genetic material of an organism by removing or altering genes within that organism, or by inserting genes from another organism
  • The organism receiving the genetic material is said to be genetically modified
    • Often referred to as 'GM' or a transgenic organism
  • The DNA of the organism that now contains DNA from another organism as well is known as recombinant DNA
  • There are many examples of genetically modified organisms, including:
    • The gene for human insulin has been inserted into bacteria, which then produce human insulin that can be collected and purified for medical use for diabetics
    • Crop plants, such as wheat and maize, have been genetically modified to contain a gene from a bacterium that produces a poison that kills insects, making them resistant to insect pests such as caterpillars
    • Crop plants have also been genetically modified to make them resistant to certain herbicides (chemicals that kill plants), meaning that when the herbicide is sprayed on the crop it only kills weeds and does not affect the crop plant
    • Some crops have been genetically modified to produce additional vitamins, e.g. ‘golden rice’ contains genes from another plant and a bacterium which make the rice grains produce a chemical that is turned into vitamin A in the human body, which could help prevent vitamin A deficiency in certain areas of the world

Benefits and risks of genetic engineering of food products

  • Benefits:
    • Improvement of crop yields (see above)
    • Making crops more nutritious to fight deficiency diseases
  • Risks
    • Possible spread of genes to wild plants
      • e.g. a herbicide-resistance gene getting into other plants, creating 'superweeds'
    • Unknown effects on human health of GM crops
    • Religious and ethical concerns about tampering with nature
      • Do animals suffer in the process?
      • Are we likely to go on and engineer ourselves genetically, creating a 'genetic underclass'
    • Knock-on effects on associated wildlife, reducing the biodiversity of agricultural land
    • The general level of uncertainty about genetic engineering and the possible unforeseen complications that it might uncover

Exam Tip

The key point about genetic engineering is that a GM organism contains DNA that would normally not be present in their species, and the point of GM is to give organisms new capabilities for humans' gain. 



  • 1.Cell Level Systems
    • 1.1 Cell Structures
      • 1.1.1 Light Microscopes
        • 1.1.2 Cell Structure
          • 1.1.3 Electron Microscopes
          • 1.2 What Happens in Cells (& What do Cells Need?)
            • 1.2.1 DNA Structure
              • 1.2.2 The Mechanism of Enzyme Action
              • 1.3 Respiration
                • 1.3.1 Respiration is a Chemical Process
                  • 1.3.2 Aerobic & Anaerobic Respiration
                    • 1.3.3 Biological Molecules
                      • 1.3.4 Tests for Biological Molecules
                      • 1.4 Photosynthesis
                        • 1.4.1 Photosynthetic Organisms as Producers
                          • 1.4.2 The Effect of 3 Factors on Photosynthesis
                            • 1.4.3 Limiting Factors - Photosynthesis
                          • 2. Scaling Up
                            • 2.1 Supplying the Cell
                              • 2.1.1 Cellular Transport - Diffusion & Osmosis
                                • 2.1.2 Cellular Transport - Active Transport
                                  • 2.1.3 Mitosis & the Cell Cycle
                                    • 2.1.4 Cell Differentiation
                                      • 2.1.5 Stem Cells in Animals & Plants
                                        • 2.1.6 Embryonic & Adult Stem Cells in Animals
                                        • 2.2 The Challenges of Size
                                          • 2.2.1 Surface Area: Volume Ratio & Transport
                                            • 2.2.2 Transport Into & Out of Organisms
                                              • 2.2.3 The Heart
                                                • 2.2.4 Blood Vessels
                                                  • 2.2.5 Blood Composition
                                                    • 2.2.6 Transport of Water & Mineral Ions in Plants
                                                      • 2.2.7 Transpiration & Translocation
                                                        • 2.2.8 Xylem & Phloem
                                                          • 2.2.9 Affecting Water Uptake by a Plant
                                                        • 3. Organism Level Systems
                                                          • 3.1 Coordination & Control – the Nervous System
                                                            • 3.1.1 The Nervous System - Structure
                                                              • 3.1.2 Generating a Nervous Response
                                                                • 3.1.3 The Reflex Arc
                                                                • 3.2 Coordination & Control – the Endocrine System
                                                                  • 3.2.1 Hormonal Control
                                                                    • 3.2.2 Hormones in Human Reproduction
                                                                      • 3.2.3 Four Hormones in the Menstrual Cycle
                                                                        • 3.2.4 Contraception
                                                                          • 3.2.5 Hormones to Treat Infertility
                                                                          • 3.3 Maintaining Internal Environments
                                                                            • 3.3.1 Constant Internal Environment
                                                                              • 3.3.2 Insulin in Blood Sugar Control
                                                                                • 3.3.3 Glucagon in Blood Sugar Control
                                                                                  • 3.3.4 Responses to Extremes
                                                                                • 4. Community Level Systems
                                                                                  • 4.1 Ecosystems
                                                                                    • 4.1.1 The Cycling of Materials
                                                                                      • 4.1.2 The Carbon Cycle
                                                                                        • 4.1.3 Levels of Organisation in an Ecosystem
                                                                                          • 4.1.4 Abiotic & Biotic Factors
                                                                                            • 4.1.5 Interdependence & Competition
                                                                                          • 5. Genes, Inheritance & Selection
                                                                                            • 5.1 Inheritance
                                                                                              • 5.1.1 The Genome & Genetics
                                                                                                • 5.1.2 Variation
                                                                                                  • 5.1.3 Sexual Reproduction
                                                                                                    • 5.1.4 Asexual Reproduction
                                                                                                      • 5.1.5 Inheritance
                                                                                                      • 5.2 Natural Selection & Evolution
                                                                                                        • 5.2.1 Genetic Variation Within a Population
                                                                                                          • 5.2.2 Evolution Through Natural Selection
                                                                                                            • 5.2.3 Classification
                                                                                                          • 6. Global Challenges
                                                                                                            • 6.1 Monitoring & Maintaining the Environment
                                                                                                              • 6.1.1 The Distribution & Abundance of Organisms
                                                                                                                • 6.1.2 Human Interactions Within Ecosystems
                                                                                                                  • 6.1.3 Maintaining Biodiversity
                                                                                                                  • 6.2 Feeding the Human Race
                                                                                                                    • 6.2.1 Selective Breeding of Food Products
                                                                                                                      • 6.2.2 Genetic Engineering
                                                                                                                        • 6.2.3 The Process of Genetic Engineering
                                                                                                                          • 6.2.4 Biotechnology & Human Population
                                                                                                                          • 6.3 Monitoring & Maintaining Health
                                                                                                                            • 6.3.1 Health & Disease: Disease Types
                                                                                                                              • 6.3.2 Communicable Diseases
                                                                                                                                • 6.3.3 White Blood Cells & Platelets
                                                                                                                                  • 6.3.4 Non-Specific Defences
                                                                                                                                    • 6.3.5 The Human Immune System
                                                                                                                                      • 6.3.6 Vaccines Against Disease
                                                                                                                                        • 6.3.7 Developing New Medicines
                                                                                                                                          • 6.3.8 Non-Communicable Human Diseases
                                                                                                                                            • 6.3.9 Stem Cells in Medicine
                                                                                                                                              • 6.3.10 Gene Technology in Medicine
                                                                                                                                            • 7. Practical Skills
                                                                                                                                              • 7.1 Practical Skills
                                                                                                                                                • 7.1.1 Practical - Using Light Microscopes to View Cells
                                                                                                                                                  • 7.1.3 Practical - Sampling Techniques - Quadrats
                                                                                                                                                    • 7.1.4 Practical - Investigating Enzymatic Reactions
                                                                                                                                                      • 7.1.5 Practical - Investigating Photosynthesis
                                                                                                                                                        • 7.1.6 Practical - Using a Potometer
                                                                                                                                                          • 7.1.7 Practical - Measurement of Stomatal Density
                                                                                                                                                            • 7.1.8 Practical - Aseptic Technique
                                                                                                                                                              • 7.1.9 Practical - Surface Area: Volume Ratio
                                                                                                                                                                • 7.1.2 Practical - DNA Extraction
                                                                                                                                                                  • 7.1.10 Practical - Investigating Osmosis


                                                                                                                                                                  DOWNLOAD PDF

                                                                                                                                                                Author: Phil

                                                                                                                                                                Phil graduated in Biochemistry from Birmingham University and spent seventeen years in the drinks and chemicals industries. He holds an MBA from Manchester Business School. More recently, Phil has taught in secondary schools, examined GCSE Biology and has also co-directed a tuition agency. He is a passionate believer in promoting numeracy in his teaching and loves to create innovative resources. Away from work, Phil loves to be outside, cycling, running or hiking; when relaxing indoors, he plays classical guitar.


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