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OCR Gateway GCSE Biology: Combined Science

Revision Notes

Home / GCSE / Biology: Combined Science / OCR Gateway / Revision Notes / 2. Scaling Up / 2.1 Supplying the Cell / 2.1.4 Cell Differentiation


2.1.4 Cell Differentiation


Cell Specialisation

  • Humans are made from trillions of cells, but only of about 250 different cell types
  • Specialised cells are cells that have a particular structure and composition of sub-cellular structures
    • The structural differences between different types of cells enables them to perform specific functions
    • This allows organisms to operate more efficiently
  • Cells specialise by undergoing a process known as differentiation
    • e.g. to develop into a nerve cell the cytoplasm and cell membrane of an undifferentiated cell must elongate to form connections over large distances
  • Most animal cells (except stem cells) differentiate at an early stage during development to become specialised
    • They then lose their ability to differentiate
  • The majority of plant cells never lose the ability to differentiate into specialised cell types
    • They retain the ability to fully differentiate throughout the life of a plant

Differentiation, IGCSE & GCSE Biology revision notes

Diagram showing the differentiation of a human cell

Examples of Specialised Cells

Examples of Specialised Cells in Animals Table

Examples of specialised cells in animals table, IGCSE & GCSE Biology revision notes

Ciliated Cells, IGCSE & GCSE Biology revision notes

Ciliated epithelial cells - the hair-like cilia beat to move mucus and any trapped particles

Nerve Cell, IGCSE & GCSE Biology revision notes

Nerve cells are long with extensions and branches to allow communication with other nerve cells or organs

Red Blood Cells, IGCSE & GCSE Biology revision notes

Red blood cells are biconcave and contain no nucleus to maximise transport of gasses

Sperm Cell, IGCSE & GCSE Biology revision notes

Sperm cells have a tail to enable the sperm to move

Egg Cell, IGCSE & GCSE Biology revision notes

An egg cell contains a lot of cytoplasm rich in nutrients

Examples of Specialised Cells in Plants Table

Examples of specialised cells in plants table, IGCSE & GCSE Biology revision notes

Root Hair Cell, IGCSE & GCSE Biology revision notes

Root hair cell have a large surface area to maximise absorption of water and minerals

Xylem Structure, IGCSE & GCSE Biology revision notes

Xylem cells lose their top and bottom walls to form a continuous tube through which water moves through

Palisade Mesophyll Cell, IGCSE & GCSE Biology revision notes

Palisade mesophyll cell contain many chloroplasts to help maximise photosynthesis



  • 1.Cell Level Systems
    • 1.1 Cell Structures
      • 1.1.1 Light Microscopes
        • 1.1.2 Cell Structure
          • 1.1.3 Electron Microscopes
          • 1.2 What Happens in Cells (& What do Cells Need?)
            • 1.2.1 DNA Structure
              • 1.2.2 The Mechanism of Enzyme Action
              • 1.3 Respiration
                • 1.3.1 Respiration is a Chemical Process
                  • 1.3.2 Aerobic & Anaerobic Respiration
                    • 1.3.3 Biological Molecules
                      • 1.3.4 Tests for Biological Molecules
                      • 1.4 Photosynthesis
                        • 1.4.1 Photosynthetic Organisms as Producers
                          • 1.4.2 The Effect of 3 Factors on Photosynthesis
                            • 1.4.3 Limiting Factors - Photosynthesis
                          • 2. Scaling Up
                            • 2.1 Supplying the Cell
                              • 2.1.1 Cellular Transport - Diffusion & Osmosis
                                • 2.1.2 Cellular Transport - Active Transport
                                  • 2.1.3 Mitosis & the Cell Cycle
                                    • 2.1.4 Cell Differentiation
                                      • 2.1.5 Stem Cells in Animals & Plants
                                        • 2.1.6 Embryonic & Adult Stem Cells in Animals
                                        • 2.2 The Challenges of Size
                                          • 2.2.1 Surface Area: Volume Ratio & Transport
                                            • 2.2.2 Transport Into & Out of Organisms
                                              • 2.2.3 The Heart
                                                • 2.2.4 Blood Vessels
                                                  • 2.2.5 Blood Composition
                                                    • 2.2.6 Transport of Water & Mineral Ions in Plants
                                                      • 2.2.7 Transpiration & Translocation
                                                        • 2.2.8 Xylem & Phloem
                                                          • 2.2.9 Affecting Water Uptake by a Plant
                                                        • 3. Organism Level Systems
                                                          • 3.1 Coordination & Control – the Nervous System
                                                            • 3.1.1 The Nervous System - Structure
                                                              • 3.1.2 Generating a Nervous Response
                                                                • 3.1.3 The Reflex Arc
                                                                • 3.2 Coordination & Control – the Endocrine System
                                                                  • 3.2.1 Hormonal Control
                                                                    • 3.2.2 Hormones in Human Reproduction
                                                                      • 3.2.3 Four Hormones in the Menstrual Cycle
                                                                        • 3.2.4 Contraception
                                                                          • 3.2.5 Hormones to Treat Infertility
                                                                          • 3.3 Maintaining Internal Environments
                                                                            • 3.3.1 Constant Internal Environment
                                                                              • 3.3.2 Insulin in Blood Sugar Control
                                                                                • 3.3.3 Glucagon in Blood Sugar Control
                                                                                  • 3.3.4 Responses to Extremes
                                                                                • 4. Community Level Systems
                                                                                  • 4.1 Ecosystems
                                                                                    • 4.1.1 The Cycling of Materials
                                                                                      • 4.1.2 The Carbon Cycle
                                                                                        • 4.1.3 Levels of Organisation in an Ecosystem
                                                                                          • 4.1.4 Abiotic & Biotic Factors
                                                                                            • 4.1.5 Interdependence & Competition
                                                                                          • 5. Genes, Inheritance & Selection
                                                                                            • 5.1 Inheritance
                                                                                              • 5.1.1 The Genome & Genetics
                                                                                                • 5.1.2 Variation
                                                                                                  • 5.1.3 Sexual Reproduction
                                                                                                    • 5.1.4 Asexual Reproduction
                                                                                                      • 5.1.5 Inheritance
                                                                                                      • 5.2 Natural Selection & Evolution
                                                                                                        • 5.2.1 Genetic Variation Within a Population
                                                                                                          • 5.2.2 Evolution Through Natural Selection
                                                                                                            • 5.2.3 Classification
                                                                                                          • 6. Global Challenges
                                                                                                            • 6.1 Monitoring & Maintaining the Environment
                                                                                                              • 6.1.1 The Distribution & Abundance of Organisms
                                                                                                                • 6.1.2 Human Interactions Within Ecosystems
                                                                                                                  • 6.1.3 Maintaining Biodiversity
                                                                                                                  • 6.2 Feeding the Human Race
                                                                                                                    • 6.2.1 Selective Breeding of Food Products
                                                                                                                      • 6.2.2 Genetic Engineering
                                                                                                                        • 6.2.3 The Process of Genetic Engineering
                                                                                                                          • 6.2.4 Biotechnology & Human Population
                                                                                                                          • 6.3 Monitoring & Maintaining Health
                                                                                                                            • 6.3.1 Health & Disease: Disease Types
                                                                                                                              • 6.3.2 Communicable Diseases
                                                                                                                                • 6.3.3 White Blood Cells & Platelets
                                                                                                                                  • 6.3.4 Non-Specific Defences
                                                                                                                                    • 6.3.5 The Human Immune System
                                                                                                                                      • 6.3.6 Vaccines Against Disease
                                                                                                                                        • 6.3.7 Developing New Medicines
                                                                                                                                          • 6.3.8 Non-Communicable Human Diseases
                                                                                                                                            • 6.3.9 Stem Cells in Medicine
                                                                                                                                              • 6.3.10 Gene Technology in Medicine
                                                                                                                                            • 7. Practical Skills
                                                                                                                                              • 7.1 Practical Skills
                                                                                                                                                • 7.1.1 Practical - Using Light Microscopes to View Cells
                                                                                                                                                  • 7.1.3 Practical - Sampling Techniques - Quadrats
                                                                                                                                                    • 7.1.4 Practical - Investigating Enzymatic Reactions
                                                                                                                                                      • 7.1.5 Practical - Investigating Photosynthesis
                                                                                                                                                        • 7.1.6 Practical - Using a Potometer
                                                                                                                                                          • 7.1.7 Practical - Measurement of Stomatal Density
                                                                                                                                                            • 7.1.8 Practical - Aseptic Technique
                                                                                                                                                              • 7.1.9 Practical - Surface Area: Volume Ratio
                                                                                                                                                                • 7.1.2 Practical - DNA Extraction
                                                                                                                                                                  • 7.1.10 Practical - Investigating Osmosis


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                                                                                                                                                                Author: Adam



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