Edexcel International A Level Biology

Topic Questions

The Brain

1a
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2 marks

The brain is responsible for processing information and coordinating responses.

The diagram shows a human brain.

Three regions of the brain have been labelled.

edexcel-ial-unit-5-jan-2021-q3a
Complete the table with the name and function of each region.

Label Name of the region Function of the region
P medulla oblongata  
Q    
R   balance and coordinating movement

1b
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4 marks

Seizures in the brain can be investigated using different imaging techniques.

(i)
Which one of the following statements is correct?
(1)
  A CT scans are produced by the absorbance of magnetic fields
  B CT scans are produced by the absorbance of radio waves by deoxyhaemoglobin
  C CT scans produce a cross-sectional image of a thin slice through the body
  D CT scans can be used to study brain activity while a person is
undertaking tasks

(ii)

During a seizure, part of the brain will be overactive.

Describe how positron emission tomography (PET) could be used to identify the part of the brain involved.

(3)
1c
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3 marks

Some seizures can result in an increase in body temperature.

Suggest how a seizure in part of the brain could lead to an increase in body temperature.

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2a2 marks

The scientific article you have studied is adapted from Rethinking Alzheimer’s in New Scientist (February 2019).

Use the information from the scientific article and your own knowledge to answer the following questions.

Memory and cognitive function are two processes that occur in the brain (paragraphs 2 and 13).

Different parts of the brain are responsible for specific functions.

Complete the table showing which parts of the brain are responsible for different functions.

Part of brain Function
 cerebellum  
   interpretation of information from the retina
 medulla oblongata  
   secretion of ADH
2b4 marks

Some forms of dementia can be diagnosed using brain scans.

Compare and contrast the use of functional magnetic resonance imaging (fMRI) and computed tomography (CT) scans to identify structures like plaques in the brain (paragraph 6).

2c4 marks

Suggest how the amyloid protein may prevent bacterial infection in the brain (paragraphs 7 and 22).

2d4 marks

Explain how the bacterium Porphyromonas gingivalis that causes gum disease may invade the brain and cause inflammation in brain regions affected by Alzheimer’s disease (paragraphs 10, 20 and 21).

2e3 marks

Suggest how gingipains may have a degrading effect on the memory of a person suffering from Alzheimer’s disease (paragraph 12).

2f3 marks

The team found genetic material from P. gingivalis in the cerebral cortex (paragraph 13).

Describe how the team could show that this genetic material is active.

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