5.19B The Production of Cloned Mammals (Edexcel IGCSE Biology)

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Cloning Mammals

Embryo cloning

  • It is possible to clone animals using embryo transplants
  • For example, if a farmer wants the best cattle, they must first create an offspring from the best bull and best cow, and then clone this offspring to create many genetically identical copies (clones)
  • This process is known as embryo cloning and is achieved in the following way:
    • Egg cells from the best cow are artificially fertilised using sperm cells taken from the best bull
    • This forms an embryo
    • The developing animal embryo is then split apart many times before the cells of the embryo become specialised
    • This forms many separate embryos that are genetically identical
    • These cloned embryos are then transplanted into host mothers
    • The calves born from these host mothers are all genetically identical

Embryo cloning_1, downloadable IGCSE & GCSE Biology revision notesEmbryo cloning_2, downloadable IGCSE & GCSE Biology revision notes

Embryo cloning

Adult cell cloning

  • Adult cell cloning is achieved in the following way:
    • The nucleus is removed from an unfertilised egg cell
    • The nucleus from an adult body cell, such as a skin cell, is inserted into the egg cell
    • A very small electric shock stimulates the egg cell to divide (by mitosis) to form an embryo
    • These embryo cells contain the same genetic information as the adult skin cell
    • When the embryo has developed into a ball of cells, it is inserted into the womb of an adult female (known as the surrogate mother) to continue its development until birth

  • This process was used to create the first clone (exact genetic copy) of a mammal in 1996
  • Scientists in Scotland successfully cloned an adult female sheep
  • The clone was called Dolly

adult-cell-cloning-1-downloadable-igcse-and-gcse-biology-revision-notesAdult cell cloning_2, downloadable IGCSE & GCSE Biology revision notes

Adult cell cloning: the cloning technique used to produce the first cloned mammal, Dolly the sheep

Benefits & Risks of Cloning TableBenefits and risks of cloning table, downloadable IGCSE & GCSE Biology revision notes

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Lára

Author: Lára

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.