CIE A Level Chemistry

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First teaching 2020

Last exams 2024

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7.6.10 Peptide Bonds

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Formation of Peptide Bonds

  • Each amino acid contains an amine (-NH2) and carboxylic acid (-COOH) group
  • The -NH2 group of one amino acid can react with the -COOH group of another amino acid in a condensation reaction to form a dipeptide
    • The new amide bond between two amino acids is also called a peptide link or peptide bond

  • Since this is a condensation reaction, a small molecule (in this case H2O) is eliminated
  • The dipeptide still contains an -NH2 and -COOH group at each end of the molecule which can again participate in a condensation reaction to form a tripeptide

Nitrogen Compounds - Formation of Peptide Bonds, downloadable AS & A Level Chemistry revision notes

A peptide bond is an amide bond between two amino acids

  • A polypeptide is formed when many amino acids join together to form a long chain of molecules

 

Nitrogen Compounds - Polypeptides, downloadable AS & A Level Chemistry revision notes

A polypeptide is a long chain of amino acid molecules joined together

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Author: Francesca

Fran studied for a BSc in Chemistry with Forensic Science, and since graduating taught A level Chemistry in the UK for over 11 years. She studied for an MBA in Senior Leadership, and has held a number of roles during her time in Education, including Head of Chemistry, Head of Science and most recently as an Assistant Headteacher. In this role, she used her passion for education to drive improvement and success for staff and students across a number of subjects in addition to Science, supporting them to achieve their full potential. Fran has co-written Science textbooks, delivered CPD for teachers, and worked as an examiner for a number of UK exam boards.