AQA A Level Biology

Topic Questions

6.1 Response to Stimuli (A Level only)

1a1 mark

Define the term tropism.

1b2 marks

Organisms can only survive if they are able to respond to changes in their environment.

Describe how the plant growth factor, indoleacetic acid (IAA), allows plants to respond to light stimuli from their surroundings.

1c2 marks

IAA has the opposite effect on the cells in plant roots. The growth factor is actively transported to the bottom region of the root tip where amyloplasts are located, as shown in Figure 1

Figure 1

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Explain why the amyloplasts are located at the bottom of the root tip.

1d2 marks

In an investigation to test the effect of IAA on shoot growth in seedlings, three different environments were set up:

Group A = Shoot with the tip removed.

Group B = Shoot has been covered in a light proof container.

Group C = Shoot was grown under a directional light source.

Figure 2

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Complete the diagram in Figure 2 to show what you would expect to see in the shoot which was grown under a directional light source. Remember to label the IAA molecules on your diagram.

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2a1 mark

State the key difference between kinesis and taxis.

2b1 mark

An investigation was set up as shown in Figure 1 to study kinesis and taxis in maggots. 

Figure 1

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The results showed that the maggots exhibited negative phototaxis. 

Suggest what observation was made to reach this conclusion.

2c1 mark

The diagram in Figure 2 represents the route of a nervous impulse through the nervous system.

Figure 2

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Identify the feature in Figure 2 which suggests this is a simple reflex arc.

2d3 marks

Identify the junctions labelled A and B in Figure 2 and give one key difference between them.

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3a1 mark

Cardiac muscle cells are said to be myogenic.

Define myogenic.

3b3 marks

Use Figure 1 to describe the path of electrical activity through the cardiac muscle that leads to the smooth contraction of the heart.

Figure 1

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3c1 mark

Identify the receptors located within the cardioregulatory centre of the brain that are involved in controlling heart rate.

3d2 marks

When stimulated the sympathetic and parasympathetic nerves have different effects on an individual's heart rate.

State the effect of each.

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4a3 marks

A Pacinian corpuscle detects pressure changes in the skin.

Describe the structure of a Pacinian corpuscle.

4b3 marks

Describe how the stretch-mediated sodium ion channels facilitate the establishment of a generator potential when pressure is applied to the Pacinian corpuscle.

4c2 marks

Table 1 shows the changes in membrane potential of a sensory neurone when different pressures were applied to the associated Pacinian corpuscle.

Table 1

Pressure applied to the Pacinian corpuscle

Membrane potential of the sensory neurone / mV

None

-70

Light

-70

Medium

+40

Heavy

+40

The membrane potential produced in the sensory neurone as a result of medium and heavy pressure indicates that an action potential has been triggered.

Explain why the membrane potential was identical despite different intensities of pressure being applied.

4d2 marks

It is possible to investigate the habituation and resolution of touch receptors in the skin.

State what is meant by the term habituation with reference to touch receptors.

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5a3 marks

Figure 1 shows the structures of the human eye.

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State the name and function of the components labelled A-C.

5b2 marks

The human retina contains approximately 125 million rod cells and 7 million cone cells. 

Calculate the ratio of rods to cones.

5c2 marks

Describe how the summation of rod cells provides an advantage to nocturnal animals.

5d2 marks

Suggest why the fovea provides vision with higher acuity than the rest of the retina.

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1a2 marks

A researcher investigated the effects of light levels on the behaviour of woodlice.They set up their experiment as shown in Figure 1 below.

Figure 1

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The researcher carried out the following procedure:

-   Placed 8 woodlice carefully into the petri dish

-   Set up the lamp (LED bulb doesn’t give off heat) at a specified distance from the petri dish before switching the lamp on      

-   Left the dish for 10 minutes

-   Counted the number of woodlice that remained stationary during the course of 1 minute

-   Repeated the same procedure twice more with a different group of 8 woodlice

-   Repeated the procedure with the lamp at different distances from the dish

Explain why the researcher left the dish for 10 minutes before recording any results.

1b2 marks

The results gained by the researcher are shown in figure 2 below.

Figure 2

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Calculate the percentage increase in woodlice that are not moving when the light is 80cm away from the petri dish in comparison to when it is 10cm away from the dish. 

1c3 marks

Explain the results shown in Figure 2.

1d3 marks

The researcher concluded from this experiment that woodlice prefer dark conditions.  

Evaluate this conclusion. 

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2a4 marks

Plants respond to external stimuli to maximise their growth rate.  Figure 1 below shows how a plant responds to gravity.

Figure 1

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Explain what is happening at the point labelled X to cause the response shown. Refer to the diagram in your answer.

2b2 marks

Plant growth is regulated by growth factors. These are produced by cells in the growing tip of the shoot before being transported to the roots. Use your knowledge of plant and cell transport to suggest how growth factors might reach cells in the plant roots.

2c2 marks

One mechanism that plants could use to sense the direction of gravity is known as the starch-statolith hypothesis, illustrated in Figure 2 below.  

Figure 2

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g = direction of gravity, N = nucleus, V = permanent vacuole, A = starch grains, also known as statoliths.

Use Figure 2 to suggest how the starch-statolith hypothesis explains plant cells’ ability to detect the direction of gravity.

2d2 marks

In an investigation, scientists grew seedlings with a mutation that prevented them from producing starch grains. The scientists examined the roots and found that the seedlings still curved downwards, but with a reduction in root curvature in comparison to normal seedlings.  State what these results suggest about the starch-statolith hypothesis.

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3a4 marks

Figure 1 shows the changes in membrane potential taking place inside the axon of a Pacinian corpuscle when it is stimulated with increasing levels of force.  Line A represents the lowest level of force, increasing up to the maximum for line C.

Figure 1

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Explain how stimulation of the Pacinian corpuscle leads to the changes seen in line C.

3b2 marks

Explain the differences shown in Figure 1.

3c4 marks

Pacinian corpuscles are one of several different types of sensory receptors found in the skin. They are an example of what is known as a fast-adapting receptor, while some other types of receptors are described as slow adapting.  Figure 2 below shows the different responses of fast and slow adapting receptors to the same stimulus.

Figure 2

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Use Figure 2 to describe the difference in response of Pacinian corpuscles and slow-adapting receptors and suggest the difference between their roles.

3d2 marks

Pacinian corpuscles are found in mammals, while a very similar highly-sensitive, fast-adapting receptor known as a Herbst corpuscle is found in birds. Herbst corpuscles are found in high numbers in the wing tips of many species, the bills of ducks, the legs of herons, and the tongues of woodpeckers.  

Suggest how the distribution of these receptors is an advantage to birds.

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4a3 marks

Figure 1 provides information about the distribution of different photoreceptors across the retina of the human eye.

Figure 1

figure-7

Use Figure 1 to describe and explain how the colour of an image formed at point A would differ from an image formed at point B.

4b4 marks

A rare eye condition known as cone-rod dystrophy is caused by slow degeneration of the photoreceptors in the eye.  In the early stages of the condition, most cell degeneration takes place at point B (see Figure 1) before progressing later to the outer parts of the retina.  Suggest and explain how the symptoms of cone-rod dystrophy might present over time. 

4c2 marks

The number of rods cells on the human retina averages at 90,000 cells per mm2.  The diameter of the retina is 32mm.  

Use this information and the formula provided to calculate the total number of rod cells found on the retina.  

Area of a circle = πr2

4d3 marks

Rod and cone cells are unusual receptors, in that they are in a depolarised state while in the dark, and they become hyperpolarised when stimulated.  The flow diagram in Figure 2 shows the sequence of events that take place when light falls on a rod cell.

Figure 2

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Use the information provided in Figure 2 to suggest how this sequence of events leads to the hyperpolarisation of rod cells.

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5a3 marks

A condition known as sinus node dysfunction can result when a specific type of tissue in the heart is replaced by fibrous connective tissue.  Suggest how this could cause problems for impulse initiation and transmission within the heart.

5b3 marks

One symptom of sinus node dysfunction is bradycardia, or a slow heart rate.  One treatment for bradycardia is to take a drug called atropine.  The effects of atropine, along with some other chemicals, on the heart rate of frogs is shown in Figure 1 below.

Figure 1

figure-9

Describe the effect that atropine has when administered alongside acetylcholine.  Suggest an explanation for this.

5c2 marks

A student concluded from the graph that epinephrine would be a better treatment for bradycardia in humans than atropine. Evaluate their conclusion.

5d5 marks

Epinephrine (see Figure 1) is also known as adrenaline.  

Explain the role played by adrenaline in the control of heart rate.

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1a2 marks

IAA is a specific growth factor found in plants and has a vital role in the growth and development of plant tissues. It moves from the growing regions of a plant shoot to other tissues via diffusion. When light is shone on a young shoot from one side, IAA will stimulate growth on the shaded side. Explain how growth on the shaded side of a young shoot helps to keep the leaves in a favourable environment for survival.

1b3 marks

Substance X is a synthetic substance that has a similar effect to that of IAA. It is used commercially to help control the growth of cultivated plants. Scientists investigated the effect of temperature on the uptake and absorption of substance X. A solution containing substance X was sprayed on the lower surface of leaves and the base of stems (so it would be taken up by the roots). The plants were kept in a greenhouse.
Figure 1 shows the results.

Figure 1

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Describe and explain the effect of temperature on the rate at which substance X is taken up by the roots.

1c2 marks

The scientists sprayed the solution on the lower surface of the leaves. Using your knowledge of the properties of leaves, suggest why they did this.

1d2 marks

In this investigation, the scientists investigated the leaves of apple trees at a particular time in the year. Suggest two reasons why the results might be different for different times of the year.

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2a2 marks

A builder accidentally cuts his finger on an exposed nail protruding from a piece of wood. He immediately pulls his finger away. This reaction occurs due to a simple reflex are involving three neurones.

Figure 1 shows the pathway involved in this reaction.

Figure 1

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(i)
Name the three neurones involved in the simple reflex arc.

(ii)
Name Z.
2b3 marks

Suggest three advantages of simple reflexes.

2c2 marks

Describe and explain two ways in which an axon may be adapted to conduct impulses at a faster rate in the nervous system.

2d2 marks

Synapses ensure that nerve impulses travel unidirectionally towards a muscle fibre. Explain how.

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3a2 marks

Pacinian corpuscles are one of many receptors found in the skin, they respond to changes in pressure. A scientist wanted to research the effects of different pressures on the magnitude of membrane potentials generated. They investigated this effect by connecting multiple microelectrodes to the end of a toe and applying different pressures to the toe. The microelectrodes measured the maximum membrane potential of the pacinian corpuscle and its sensory neurone when different pressures were applied. Figure 1 below shows the structure of the Pacinian corpuscle, along with its sensory neurone and the position of the microelectrodes. 

Figure 1

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Table 1 below shows the results.

Table 1

Pressure applied to the end of the toe

Membrane potential at A
(mV)
Membrane potential at B (mV)

None 

-70

-70

Light 

-45

-70

Medium

+35

+40

Heavy

+40

+40

Explain how the sensory neurone maintains a resting potential when no pressure is applied.

3b3 marks

Explain the mechanism by which the application of pressure to the Pacinian corpuscle in the toe produces the changes in membrane potential recorded by microelectrode A.

3c2 marks

The membrane potential at microelectrode B was identical for both medium and heavy pressure. Explain why.

3d2 marks

Demyelination describes the destruction of myelin surrounding axonal fibres. It is caused by diseases that damage the myelin sheath or the cells that form it. Dysmyelination refers to abnormal and defective myelin sheath. It often occurs due to hereditary mutations that affect the synthesis and formation of myelin. Explain how a lack of functional myelin can result in slower responses to stimuli.

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4a6 marks

A student undertakes some moderate exercise by walking around a football pitch. Explain what causes her heart rate to increase while she walks.

4b3 marks

An electrocardiogram (ECG) measures the electrical fluctuation within a cardiac muscle as a heart is beating. Figure 1 below shows an ECG trace for a normal, healthy person and an ECG trace for a person suffering from heart disease.

Figure 1

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Describe the path that electrical impulses follow when they are transmitted from the sinoatrial node to the ventricular muscles in a healthy heart.

4c2 marks

Explain how the information from Figure 1 suggests that the damage caused to the diseased heart is likely to have affected the sinoatrial node (SAN).

4d2 marks

Exercise can temporarily elevate an individual’s heart rate. Name two legal substances that may cause an individual's heart rate to increase for a period of time .

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5a2 marks

A research scientist wanted to investigate the behaviour of a species of woodlice that lives in soil. She cultured three samples of woodlice in three separate boxes of soil for 4 months. Each box contained an adequate food supply but were kept at a different temperatures.The temperatures used were 15 °C, 20 °C and 25 °C.

The food was removed from the boxes for 6 hours and then the woodlice were transferred onto a glass surface where there was no food. Each surface had a temperature gradient across it. After 1 hour, the research scientist recorded the position of each woodlouse.

Figure 1 below shows the results. ◼️ marks where she released the worms onto the glass surface.

Figure 1

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The research scientist concluded that the woodlice demonstrated taxis. How do the results support this conclusion?

5b3 marks

Suggest an explanation for the worms’ behaviour on the glass surfaces that lack a food source.

5c3 marks

For the entire duration of the experiment, the surfaces were exposed to light that was dim and even, just enough so the research scientist could see where the woodlice went. Apart from seeing where the woodlice moved, suggest three reasons why it was important that the light was both dim and even.

5d1 mark

Plants do not possess a nervous system yet they are still able to grow/move in response to certain stimuli. Describe what plants use in place of a nervous system.

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