CIE A Level Biology

Topic Questions

Syllabus Edition

First teaching 2020

Last exams 2024

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8.1 The Circulatory System

1a
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2 marks

Fig.1 compares the structure of two main human blood vessels.

6-2-easy-q2a

Fig.1

(i)

Identify blood vessel A.

[1]

(ii)

State a reason for your answer in part (i).

[1]

1b
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2 marks

Blood vessel B has a very large lumen.

(i)

Identify blood vessel B.

[1]

(ii)

State one reason for the presence of a large lumen in blood vessel B.

[1]

1c
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2 marks

The flow of blood in veins is not assisted by the pressure generated by the beating of the heart.

List two structures that assist with the flow of blood in veins.

1d
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1 mark

The diagram represents a mammalian circulatory system. Mammals have two separate circulations that supply blood to different organs.

State the name of the circulation that blood vessels T and S form part of.

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2a
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2 marks

Fig. 1 shows a blood vessel with two types of blood cell moving through.

lymphocyte-and-rbc-in-a-capillary-sq

Fig. 1

Name the cells labelled X and Y in Fig. 1. Justify your answer.

2b
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3 marks

With reference to Fig.1, state three ways in which cell X is different to cell Y.

2c
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5 marks

Blood has many components. Plasma is a straw coloured liquid which gives blood its fluidity and is made up primarily of water.

(i)

Identify two properties of water which make it ideal as a main component of blood.

[2]

(ii)

State three substances that are transported in blood plasma.

[3]
2d
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2 marks

Give the evidence seen in Fig.1 which identifies the blood vessel as a capillary.

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3a
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2 marks

Exchange of substances between cells and blood occurs via the tissue fluid, shown in Fig.1.SfWlspR~_tissue-fluid-formation-sq

Fig. 1

Tick the boxes which correctly describe the conditions inside the capillary at positions A and B in Fig.1.

 

High hydrostatic pressure

low hydrostatic pressure

Water moves out

 Water moves in

A

       

B

       

3b
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3 marks

Fig.1 shows another vessel labelled C.

(i)

Give the name of vessel C.

[1]

(ii)

Name two substances which enter vessel C from the surrounding tissues.

[2]

3c
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2 marks

The following table shows the mean pressure (in mmHg) measured in different blood vessels of the body.

Blood vessel Mean blood pressure / mmHg
Aorta 94
Arteries 90
Arterioles 68
Capillaries 24
Venules 10
Veins 3
Vena Cava 2

Calculate the percentage difference between the mean blood pressure of the aorta and vena cava.

Show your working and give your answer to three significant figures.

3d
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2 marks

Describe how the circulatory system maintains one way flow around the body

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1a
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2 marks

Scientists collected red blood cell samples from four different mammals; cats, rats, hares and goats. The samples were placed in different concentrations of sodium chloride solution for a set amount of time and the percentage of haemolysed (burst) red blood cells was measured at each sodium chloride concentration. Fig. 1 shows the results of the above experiment.

8-1-fig-3-1
Fig. 1

The scientists used a colorimeter to measure the percentage of haemolysed red blood cells.

Suggest why a colorimeter could be used to measure this.

1b
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3 marks

Contrast the results for the red blood cells of the goat and the rat.

1c
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4 marks

Explain the results shown for the cat in Fig. 1 at the following sodium chloride concentrations:

(i)
0 %

[2]

(ii)
0.38 %

[2]

1d
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3 marks

Fig. 2 shows a microscope image of a mammalian blood sample.

8-1-fig-3-2
Fig. 2

(i)
Identify the cell types represented by cells X and Y in Fig. 2.

[1]

(ii)
Explain your answer to part (i).

[2]

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2a
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3 marks

Fig. 1 represents a capillary as it passes through the tissues of the body along with the surrounding tissue fluid.

8-1-fig-4-1
Fig. 1

Give three differences between the composition of the blood at the arteriole end of the capillary and the venule end.

2b
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4 marks

Use Fig. 1 to explain the formation of tissue fluid and its return to the capillary.

2c
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2 marks

Protein deficiency in an individual's diet can influence the return of tissue fluid to the capillaries.

Suggest and explain one tissue fluid-related symptom of dietary protein deficiency.

2d
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2 marks

The main component of both blood and tissue fluid is water.

Explain how one property of water makes it an ideal transport medium for organisms with a transport system.

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3a
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2 marks

Based on your knowledge of diffusion, explain why multicellular organisms need a specialised transport system.

3b
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3 marks

Fig. 1 shows two organs of the mammalian circulatory system.

Artery and vein structure

Fig. 1

(i)

Identify the organs labelled X and Y

[1]

(ii)

Explain the evidence shown in Fig. 1 that determined your answer to part (i).

[2]

3c
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1 mark

Fig. 2 shows a biological drawing of organ X

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Fig. 2

Describe the errors contained within this drawing.

3d
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5 marks

The heart, contains two blood vessels that transport blood via the lungs. 

(i)

Give the name of these two blood vessels. 

[1]

(ii)

Explain the movement of blood between the heart and the lungs. Do not include details of the cardiac cycle as part of your answer.

[4]

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1a
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2 marks

Fig. 1 shows a series of red blood cells passing through a capillary in the tissues. The magnification factor of Fig. 1 is x6000.

8-1-fig-1-1Fig. 1

The length of the line marked X in the image shown in Fig. 1 is 4.6 cm.

Calculate the actual diameter of the red blood cell marked X in Fig. 1 Show your working and give your answer in µm to one decimal place.

1b2 marks

State and explain one feature of capillaries visible in Fig. 1 that helps them to carry out their function.

1c3 marks

Research suggests that in patients with diabetes mellitus red blood cell membranes can harden, reducing the ability of red blood cells to deform and flex.

Suggest and explain the possible symptoms that this could cause in diabetic patients.

1d2 marks

Red blood cells and capillaries form part of the circulatory system of some organisms.

Explain why multicellular organisms, such as humans, require a circulatory system while single-celled organisms, such as bacteria, do not.

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2a1 mark

Fig.1 shows an image of a micrograph of a cross section through a mammalian blood vessel.

8-1-fig-2-1Fig. 1

Identify the type of blood vessel shown in Fig.1.

2b4 marks

Explain how the blood vessel shown in Fig.1 is adapted to carry out its function.

2c2 marks

Fig. 2 shows pressure changes in the blood vessels as the blood passes through different sections of the mammalian circulatory system.

8-1-fig-2-2
Fig. 2

Explain the need for a separate systemic and pulmonary circulation in mammals. 

2d5 marks

Explain the blood pressure in the following sections of Fig. 2

(i)
The arteries and arterioles

[3]

(ii)
The capillaries

[1]

(iii)
The venules and veins

[1]

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