CIE A Level Biology (9700) exams from 2022

Revision Notes

12.2.2 The Four Stages in Aerobic Respiration

The Four Stages in Aerobic Respiration

  • Glucose is the main respiratory substrate used by cells
  • Aerobic respiration is the process of breaking down a respiratory substrate in order to produce ATP using oxygen
  • The process of aerobic respiration using glucose can be split into four stages
  • Each stage occurs at a particular location in a eukaryotic cell:
    • Glycolysis takes place in the cell cytoplasm
    • The Link reaction takes place in the matrix of the mitochondria
    • The Krebs cycle takes place in the matrix of the mitochondria
    • Oxidative phosphorylation occurs at the inner membrane of the mitochondria

Four stages of respiration table

Four Stages of Respiration Table, downloadable AS & A Level Biology revision notes

Exam Tip

It’s important to know the exact locations of each stage. It is not enough to say the Krebs cycle takes place in the mitochondria, you need to say it takes place in the matrix of the mitochondria.

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Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.
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