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OCR Gateway GCSE Biology

Revision Notes

Home / GCSE / Biology / OCR Gateway / Revision Notes / 6. Global Challenges / 6.3 Monitoring & Maintaining Health / 6.3.11 Stem Cells in Medicine


6.3.11 Stem Cells in Medicine


Stem Cells in Medicine

  • It is possible to grow human embryos in the lab and to extract embryonic stem cells from them
  • These embryonic stem cells can then be encouraged to differentiate into most types of specialised cell
  • Scientists and doctors could use stem cell technology to repair damaged organs by growing new tissue from stem cells produced by embryos created using genetic information from the patient
  • Adult stem cells can also be cultured in the lab and made to differentiate into specialised cells
    • They can only differentiate into a few cell types (predominantly cells of the blood)
  • Stem cells could be used to cure many diseases in the future, such as diabetes and paralysis

Stem Cells Table

Stem cells table 1, downloadable IGCSE & GCSE Biology revision notes

Stem cells in therapeutic cloning

  • In therapeutic cloning, an embryo is produced with the same genes as the patient
  • A 5-day old embryo is the best source of embryonic stem cells
  • Stem cells from embryos created in this way are not rejected by the patient's body
  • So they may be used for medical treatment without the patient having to take drugs to suppress their immune system (which reduce the body's ability to fight infection)

Therapeutic Cloning, downloadable IGCSE & GCSE Biology revision notes

The process of therapeutic cloning

Evaluating stem cells in medicine

Evaluating Stem Cells in Medicine Table

Evaluating stem cells_1, downloadable IGCSE & GCSE Biology revision notes

Exam Tip

Despite the many advantages of using embryonic stem cells, the main factors against using them are ethical and logistical. Firstly, they are a human life in many peoples' view, for people that believe life starts at fertilisation. Secondly, despite the plentiful supply of sperm for IVF treatments, eggs are much harder to get out of a person's body. A woman has to undergo painful and expensive hormone therapy to produce eggs, then have an operation under sedation to have them removed.



  • 1. Cell Level Systems
    • 1.1 Cell Structures
      • 1.1.1 Light Microscopes
        • 1.1.2 Cell Structure
          • 1.1.3 Electron Microscopes
          • 1.2 What Happens in Cells (& What do Cells Need?)
            • 1.2.1 DNA Structure
              • 1.2.2 Nucleotides
                • 1.2.3 Protein Synthesis
                  • 1.2.4 The Mechanism of Enzyme Action
                  • 1.3 Respiration
                    • 1.3.1 Respiration is a Chemical Process
                      • 1.3.2 Aerobic & Anaerobic Respiration
                        • 1.3.3 Biological Molecules
                          • 1.3.4 Tests for Biological Molecules
                          • 1.4 Photosynthesis
                            • 1.4.1 Photosynthetic Organisms as Producers
                              • 1.4.2 The Effect of 3 Factors on Photosynthesis
                                • 1.4.3 Limiting Factors - Photosynthesis
                              • 2. Scaling Up
                                • 2.1 Supplying the Cell
                                  • 2.1.1 Cellular Transport - Diffusion & Osmosis
                                    • 2.1.2 Cellular Transport - Active Transport
                                      • 2.1.3 Mitosis & the Cell Cycle
                                        • 2.1.4 Cell Differentiation
                                          • 2.1.5 Stem Cells in Animals & Plants
                                            • 2.1.6 Embryonic & Adult Stem Cells in Animals
                                            • 2.2 The Challenges of Size
                                              • 2.2.1 Surface Area: Volume Ratio & Transport
                                                • 2.2.2 Transport Into & Out of Organisms
                                                  • 2.2.3 The Heart
                                                    • 2.2.4 Blood Vessels
                                                      • 2.2.5 Blood Composition
                                                        • 2.2.6 Transport of Water & Mineral Ions in Plants
                                                          • 2.2.7 Transpiration & Translocation
                                                            • 2.2.8 Xylem & Phloem
                                                              • 2.2.9 Affecting Water Uptake by a Plant
                                                            • 3. Organism Level Systems
                                                              • 3.1 Coordination & Control – the Nervous System
                                                                • 3.1.1 The Nervous System - Structure
                                                                  • 3.1.2 Generating a Nervous Response
                                                                    • 3.1.3 The Reflex Arc
                                                                      • 3.1.4 The Eye
                                                                        • 3.1.5 The Brain
                                                                          • 3.1.6 Investigating Brain Function
                                                                          • 3.2 Coordination & Control – the Endocrine System
                                                                            • 3.2.1 Hormonal Control
                                                                              • 3.2.2 Thyroxine & Adrenaline
                                                                                • 3.2.3 Hormones in Human Reproduction
                                                                                  • 3.2.4 Four Hormones in the Menstrual Cycle
                                                                                    • 3.2.5 Contraception
                                                                                      • 3.2.6 Hormones to Treat Infertility
                                                                                        • 3.2.7 Plant Hormones - Tropisms
                                                                                          • 3.2.8 Use of Plant Hormones by Humans
                                                                                          • 3.3 Maintaining Internal Environments
                                                                                            • 3.3.1 Constant Internal Environment
                                                                                              • 3.3.2 The Skin in Temperature Control
                                                                                                • 3.3.3 Insulin in Blood Sugar Control
                                                                                                  • 3.3.4 Glucagon in Blood Sugar Control
                                                                                                    • 3.3.5 Osmotic Changes in Body Fluids
                                                                                                      • 3.3.6 The Kidneys
                                                                                                        • 3.3.7 ADH in Water Reabsorption
                                                                                                          • 3.3.8 Responses to Extremes
                                                                                                        • 4. Community Level Systems
                                                                                                          • 4.1 Ecosystems
                                                                                                            • 4.1.1 The Cycling of Materials
                                                                                                              • 4.1.2 The Carbon Cycle
                                                                                                                • 4.1.3 Decomposition & Decay
                                                                                                                  • 4.1.4 Levels of Organisation in an Ecosystem
                                                                                                                    • 4.1.5 Abiotic & Biotic Factors
                                                                                                                      • 4.1.6 Interdependence & Competition
                                                                                                                        • 4.1.7 Trophic Levels of Organisms
                                                                                                                          • 4.1.8 Pyramids of Biomass & Biomass Transfers
                                                                                                                        • 5. Genes, Inheritance & Selection
                                                                                                                          • 5.1 Inheritance
                                                                                                                            • 5.1.1 The Genome & Genetics
                                                                                                                              • 5.1.2 Variation
                                                                                                                                • 5.1.3 Influence of Genetic Variants on Phenotype
                                                                                                                                  • 5.1.4 Sexual Reproduction
                                                                                                                                    • 5.1.5 Asexual Reproduction
                                                                                                                                      • 5.1.6 Inheritance
                                                                                                                                        • 5.1.7 The History of Genetics
                                                                                                                                        • 5.2 Natural Selection & Evolution
                                                                                                                                          • 5.2.1 Genetic Variation Within a Population
                                                                                                                                            • 5.2.2 Evolution Through Natural Selection
                                                                                                                                              • 5.2.3 Classification
                                                                                                                                            • 6. Global Challenges
                                                                                                                                              • 6.1 Monitoring & Maintaining the Environment
                                                                                                                                                • 6.1.1 The Distribution & Abundance of Organisms
                                                                                                                                                  • 6.1.2 Human Interactions Within Ecosystems
                                                                                                                                                    • 6.1.3 Maintaining Biodiversity
                                                                                                                                                      • 6.1.4 The Impact of Environmental Changes
                                                                                                                                                      • 6.2 Feeding the Human Race
                                                                                                                                                        • 6.2.1 Food Security
                                                                                                                                                          • 6.2.2 Selective Breeding of Food Products
                                                                                                                                                            • 6.2.3 Genetic Engineering
                                                                                                                                                              • 6.2.4 The Process of Genetic Engineering
                                                                                                                                                                • 6.2.5 Biotechnology & Human Population
                                                                                                                                                                • 6.3 Monitoring & Maintaining Health
                                                                                                                                                                  • 6.3.1 Health & Disease: Disease Types
                                                                                                                                                                    • 6.3.2 Communicable Diseases
                                                                                                                                                                      • 6.3.3 Plant Disease - Detection & Identification
                                                                                                                                                                        • 6.3.4 White Blood Cells & Platelets
                                                                                                                                                                          • 6.3.5 Non-Specific Defences
                                                                                                                                                                            • 6.3.6 The Human Immune System
                                                                                                                                                                              • 6.3.7 Monoclonal Antibodies
                                                                                                                                                                                • 6.3.8 Vaccines Against Disease
                                                                                                                                                                                  • 6.3.9 Developing New Medicines
                                                                                                                                                                                    • 6.3.10 Non-Communicable Human Diseases
                                                                                                                                                                                      • 6.3.11 Stem Cells in Medicine
                                                                                                                                                                                        • 6.3.12 Gene Technology in Medicine
                                                                                                                                                                                      • 7. Practical Skills
                                                                                                                                                                                        • 7.1 Practical Skills
                                                                                                                                                                                          • 7.1.1 Practical - Using Light Microscopes to View Cells
                                                                                                                                                                                            • 7.1.2 Practical - Testing for Food Molecules
                                                                                                                                                                                              • 7.1.3 Practical - DNA Extraction
                                                                                                                                                                                                • 7.1.4 Practical - Sampling Techniques - Quadrats
                                                                                                                                                                                                  • 7.1.5 Practical - Investigating Enzymatic Reactions
                                                                                                                                                                                                    • 7.1.6 Practical - Investigating Photosynthesis
                                                                                                                                                                                                      • 7.1.7 Practical - Investigating Respiration
                                                                                                                                                                                                        • 7.1.8 Practical - Using a Potometer
                                                                                                                                                                                                          • 7.1.9 Practical - Measurement of Stomatal Density
                                                                                                                                                                                                            • 7.1.10 Practical - Aseptic Technique
                                                                                                                                                                                                              • 7.1.11 Practical - Surface Area: Volume Ratio
                                                                                                                                                                                                                • 7.1.12 Practical - Investigating Osmosis


                                                                                                                                                                                                                DOWNLOAD PDF

                                                                                                                                                                                                              Author: Phil

                                                                                                                                                                                                              Phil graduated in Biochemistry from Birmingham University and spent seventeen years in the drinks and chemicals industries. He holds an MBA from Manchester Business School. More recently, Phil has taught in secondary schools, examined GCSE Biology and has also co-directed a tuition agency. He is a passionate believer in promoting numeracy in his teaching and loves to create innovative resources. Away from work, Phil loves to be outside, cycling, running or hiking; when relaxing indoors, he plays classical guitar.


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