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OCR Gateway GCSE Biology

Revision Notes

Home / GCSE / Biology / OCR Gateway / Revision Notes / 3. Organism Level Systems / 3.1 Coordination & Control – the Nervous System / 3.1.6 Investigating Brain Function


3.1.6 Investigating Brain Function


The Challenges of Brain Treatments

Higher Tier Only
Investigating brain function

  • Developing an understanding of the brain and how it works is really important for medical advances in treating people with brain damage or disease
  • However, the brain is an incredibly complex and delicate organ and different regions can’t be studied in isolation
  • As a result, it is extremely difficult for neuroscientists to study it to find out how it works so current understanding is limited
  • Methods used to study brain function may involve:
    • Studying the brains of people that have died
    • Using MRI scans to monitor electrical activity during certain scenarios
    • Case studies of patients with brain damage or abnormal brain function and the presentation of their symptoms 
  • Some of the issues involved in investigating brain function are as follows:
    • Accidental damage could lead to speech or motor issues, or changes to personality which are permanent
    • There may be ethical considerations in studying individuals with severe brain damage who are unable to provide informed consent
    • Interpreting the results of MRI scans can be complicated and many patterns of activity are not yet understood

Treating problems with the brain

  • Our limited understanding of brain function means that treating brain damage and disease is very difficult
  • This is also true of other components of the nervous system because:
    • Many parts of the nervous system are not accessible and some regions of the brain cannot be treated at all 
    • Nervous tissue doesnt repair as readily as other body tissues meaning damage is often irreversible
    • Any potential treatment carries risks of further, potentially permanent, damage


  • 1. Cell Level Systems
    • 1.1 Cell Structures
      • 1.1.1 Light Microscopes
        • 1.1.2 Cell Structure
          • 1.1.3 Electron Microscopes
          • 1.2 What Happens in Cells (& What do Cells Need?)
            • 1.2.1 DNA Structure
              • 1.2.2 Nucleotides
                • 1.2.3 Protein Synthesis
                  • 1.2.4 The Mechanism of Enzyme Action
                  • 1.3 Respiration
                    • 1.3.1 Respiration is a Chemical Process
                      • 1.3.2 Aerobic & Anaerobic Respiration
                        • 1.3.3 Biological Molecules
                          • 1.3.4 Tests for Biological Molecules
                          • 1.4 Photosynthesis
                            • 1.4.1 Photosynthetic Organisms as Producers
                              • 1.4.2 The Effect of 3 Factors on Photosynthesis
                                • 1.4.3 Limiting Factors - Photosynthesis
                              • 2. Scaling Up
                                • 2.1 Supplying the Cell
                                  • 2.1.1 Cellular Transport - Diffusion & Osmosis
                                    • 2.1.2 Cellular Transport - Active Transport
                                      • 2.1.3 Mitosis & the Cell Cycle
                                        • 2.1.4 Cell Differentiation
                                          • 2.1.5 Stem Cells in Animals & Plants
                                            • 2.1.6 Embryonic & Adult Stem Cells in Animals
                                            • 2.2 The Challenges of Size
                                              • 2.2.1 Surface Area: Volume Ratio & Transport
                                                • 2.2.2 Transport Into & Out of Organisms
                                                  • 2.2.3 The Heart
                                                    • 2.2.4 Blood Vessels
                                                      • 2.2.5 Blood Composition
                                                        • 2.2.6 Transport of Water & Mineral Ions in Plants
                                                          • 2.2.7 Transpiration & Translocation
                                                            • 2.2.8 Xylem & Phloem
                                                              • 2.2.9 Affecting Water Uptake by a Plant
                                                            • 3. Organism Level Systems
                                                              • 3.1 Coordination & Control – the Nervous System
                                                                • 3.1.1 The Nervous System - Structure
                                                                  • 3.1.2 Generating a Nervous Response
                                                                    • 3.1.3 The Reflex Arc
                                                                      • 3.1.4 The Eye
                                                                        • 3.1.5 The Brain
                                                                          • 3.1.6 Investigating Brain Function
                                                                          • 3.2 Coordination & Control – the Endocrine System
                                                                            • 3.2.1 Hormonal Control
                                                                              • 3.2.2 Thyroxine & Adrenaline
                                                                                • 3.2.3 Hormones in Human Reproduction
                                                                                  • 3.2.4 Four Hormones in the Menstrual Cycle
                                                                                    • 3.2.5 Contraception
                                                                                      • 3.2.6 Hormones to Treat Infertility
                                                                                        • 3.2.7 Plant Hormones - Tropisms
                                                                                          • 3.2.8 Use of Plant Hormones by Humans
                                                                                          • 3.3 Maintaining Internal Environments
                                                                                            • 3.3.1 Constant Internal Environment
                                                                                              • 3.3.2 The Skin in Temperature Control
                                                                                                • 3.3.3 Insulin in Blood Sugar Control
                                                                                                  • 3.3.4 Glucagon in Blood Sugar Control
                                                                                                    • 3.3.5 Osmotic Changes in Body Fluids
                                                                                                      • 3.3.6 The Kidneys
                                                                                                        • 3.3.7 ADH in Water Reabsorption
                                                                                                          • 3.3.8 Responses to Extremes
                                                                                                        • 4. Community Level Systems
                                                                                                          • 4.1 Ecosystems
                                                                                                            • 4.1.1 The Cycling of Materials
                                                                                                              • 4.1.2 The Carbon Cycle
                                                                                                                • 4.1.3 Decomposition & Decay
                                                                                                                  • 4.1.4 Levels of Organisation in an Ecosystem
                                                                                                                    • 4.1.5 Abiotic & Biotic Factors
                                                                                                                      • 4.1.6 Interdependence & Competition
                                                                                                                        • 4.1.7 Trophic Levels of Organisms
                                                                                                                          • 4.1.8 Pyramids of Biomass & Biomass Transfers
                                                                                                                        • 5. Genes, Inheritance & Selection
                                                                                                                          • 5.1 Inheritance
                                                                                                                            • 5.1.1 The Genome & Genetics
                                                                                                                              • 5.1.2 Variation
                                                                                                                                • 5.1.3 Influence of Genetic Variants on Phenotype
                                                                                                                                  • 5.1.4 Sexual Reproduction
                                                                                                                                    • 5.1.5 Asexual Reproduction
                                                                                                                                      • 5.1.6 Inheritance
                                                                                                                                        • 5.1.7 The History of Genetics
                                                                                                                                        • 5.2 Natural Selection & Evolution
                                                                                                                                          • 5.2.1 Genetic Variation Within a Population
                                                                                                                                            • 5.2.2 Evolution Through Natural Selection
                                                                                                                                              • 5.2.3 Classification
                                                                                                                                            • 6. Global Challenges
                                                                                                                                              • 6.1 Monitoring & Maintaining the Environment
                                                                                                                                                • 6.1.1 The Distribution & Abundance of Organisms
                                                                                                                                                  • 6.1.2 Human Interactions Within Ecosystems
                                                                                                                                                    • 6.1.3 Maintaining Biodiversity
                                                                                                                                                      • 6.1.4 The Impact of Environmental Changes
                                                                                                                                                      • 6.2 Feeding the Human Race
                                                                                                                                                        • 6.2.1 Food Security
                                                                                                                                                          • 6.2.2 Selective Breeding of Food Products
                                                                                                                                                            • 6.2.3 Genetic Engineering
                                                                                                                                                              • 6.2.4 The Process of Genetic Engineering
                                                                                                                                                                • 6.2.5 Biotechnology & Human Population
                                                                                                                                                                • 6.3 Monitoring & Maintaining Health
                                                                                                                                                                  • 6.3.1 Health & Disease: Disease Types
                                                                                                                                                                    • 6.3.2 Communicable Diseases
                                                                                                                                                                      • 6.3.3 Plant Disease - Detection & Identification
                                                                                                                                                                        • 6.3.4 White Blood Cells & Platelets
                                                                                                                                                                          • 6.3.5 Non-Specific Defences
                                                                                                                                                                            • 6.3.6 The Human Immune System
                                                                                                                                                                              • 6.3.7 Monoclonal Antibodies
                                                                                                                                                                                • 6.3.8 Vaccines Against Disease
                                                                                                                                                                                  • 6.3.9 Developing New Medicines
                                                                                                                                                                                    • 6.3.10 Non-Communicable Human Diseases
                                                                                                                                                                                      • 6.3.11 Stem Cells in Medicine
                                                                                                                                                                                        • 6.3.12 Gene Technology in Medicine
                                                                                                                                                                                      • 7. Practical Skills
                                                                                                                                                                                        • 7.1 Practical Skills
                                                                                                                                                                                          • 7.1.1 Practical - Using Light Microscopes to View Cells
                                                                                                                                                                                            • 7.1.2 Practical - Testing for Food Molecules
                                                                                                                                                                                              • 7.1.3 Practical - DNA Extraction
                                                                                                                                                                                                • 7.1.4 Practical - Sampling Techniques - Quadrats
                                                                                                                                                                                                  • 7.1.5 Practical - Investigating Enzymatic Reactions
                                                                                                                                                                                                    • 7.1.6 Practical - Investigating Photosynthesis
                                                                                                                                                                                                      • 7.1.7 Practical - Investigating Respiration
                                                                                                                                                                                                        • 7.1.8 Practical - Using a Potometer
                                                                                                                                                                                                          • 7.1.9 Practical - Measurement of Stomatal Density
                                                                                                                                                                                                            • 7.1.10 Practical - Aseptic Technique
                                                                                                                                                                                                              • 7.1.11 Practical - Surface Area: Volume Ratio
                                                                                                                                                                                                                • 7.1.12 Practical - Investigating Osmosis


                                                                                                                                                                                                                DOWNLOAD PDF

                                                                                                                                                                                                              Author: Ruth

                                                                                                                                                                                                              Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. With 10 years of teaching experience across the 3 key science disciplines, Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.


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